Prehabilitation Postoperative Training Fitness Surgical Outcome
The association between physical fitness and outcome following major surgery is well described – less fit patients having a higher incidence of perioperative morbidity and mortality. This has led to the idea of physical training (exercise training) as a perioperative intervention with the aim of improving postoperative outcome. Studies have started to explore both preoperative training (pre- habilitation) and postoperative training (rehabilitation). We have reviewed the current literature regarding the use of prehabilitation and rehabilitation in relation to major surgery in elderly patients. We have focused particularly on randomized controlled trials, systematic reviews and meta-analyses. There is currently a paucity of high-quality clinical trials in this area, and the evidence base in elderly patients is particularly limited. The review indicated that prehabilitation can improve objectively measured fitness in the short time available prior to major surgery. Furthermore, for several general surgical procedures, prehabilitation using inspiratory muscle training may reduce the risk of some specific complications (e.g., pulmonary complications and predominately atelectasis), but it is unclear whether this translates into an improvement in overall surgical outcome. There is clear evidence that rehabilitation is of benefit to patients following cancer diagnoses, in terms of physical activity, fatigue and health-related quality of life. However, it is uncertain whether this improved physical function translates into increased survival and delayed disease recurrence. Prehabilitation using continuous or interval training has been shown to improve fitness but the impact on surgical outcomes remains ill defined. Taken together, these findings are encouraging and support the notion that pre- and postoperative exercise training may be of benefit to patients. There is an urgent need for adequately powered randomized control studies
This article reinforces the clear benefits for senior patients of preoperative preparation using exercises as medicine. Exercise has the potential to increase the speed of recovery and strengthens the breathing muscles to lessen the likelihood for pneumonia.
* Corresponding author. Tel.: þ44 151 5295882; Fax: þ44 1515295888. E-mail addresses: [email protected] (S. Jack), [email protected], [email protected] (M. West), [email protected] soton.ac.uk (M.P.W. Grocott).
1521-6896/$ – see front matter Ó 2011 Elsevier Ltd. All rights reserved. doi:10.1016/j.bpa.2011.07.003
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462 S. Jack et al. / Best Practice & Research Clinical Anaesthesiology 25 (2011) 461–472
S. Jack, MSc PhD, Consultant Clinician Scientist a,*, M. West, MD MRCS, Clinical Research Fellowa, M.P.W. Grocott, BSc MBBS MD FRCA FRCP, Professor of Anaesthesia and Critical Care Medicine b a Aintree University Hospitals NHS Foundation Trust, Department of Respiratory Research, Clinical Science Centre, Liverpool,
Merseyside L9 7A, UK b Anaesthesia and Critical Care Research Unit, University of Southampton, Southampton, UK